Overview clinical studies

Overview clinical studies

All clinical studies

NCT ID Research Preclin Phase 1 Phase 2 Phase 3
Colorectal Cancer
03750786 AGENT
ISO-CC-007, Phase III. Pivotal study with 490 patients has undergoing first line treatment for metastatic colorectal cancer (mCRC).
Ongoing
01681472 ISO-CC-002, a Phase I/II Pharmacockinetics and pharmacodynamics clinical investigation of arfolitixorin (Modufolin®) in Plasma, Tumor and Adjacent Mucosa in Patients with Colon Cancer.
Completed
01397305 ISO-MC-091, Phase I/II Study where Pemetrexed is co-administered with arfolitixorin (Modufolin®) to newly diagnosed, non-cytostatically-treated patients with resectable Rectal Cancer.
Completed
02244632 ISO-CC-005, Phase I/II arfolitixorin (Modufolin®) in Combination with 5-Fluorouracil Alone or with Irinotecamn or Oxaliplatin ± bevacizumab in patients with colorectal cancer.
Completed
Osteosarcoma.
02383901 ISO-MTX-OB1, A Retrospective Non-intervention Study tto investigate how rescue treatment with folates in patients with osteosarcoma works in clinical context.
Completed
01987102 ISO-MTX-003, Phase I/II study intended to identify the arfolitixorin (Modufolin®) dose to be used in continued clinical development for in the osteosarcoma indication.
Completed