Summary clinical studies

Summary clinical studies

All clinical studies

NCT IDResearchPreclinPhase 1Phase 2Phase 3
Colorectal Cancer
03750786AGENT
ISO-CC-007, Phase III. Pivotal study with 440 patients undergoing first line treatment for metastatic colorectal cancer (mCRC). Clinical Trial >>
Ongoing
01681472ISO-CC-002, a Phase I/II Pharmacockinetics and pharmacodynamics clinical investigation of arfolitixorin (Modufolin®) in Plasma, Tumor and Adjacent Mucosa in Patients with Colon Cancer. Clinical Trial >>
Completed
01397305ISO-MC-091, Phase I/II Study where Pemetrexed is co-administered with arfolitixorin (Modufolin®) to newly diagnosed, non-cytostatically-treated patients with resectable Rectal Cancer. Clinical Trial >>
Completed
02244632ISO-CC-005, Phase I/II arfolitixorin (Modufolin®) in Combination with 5-Fluorouracil Alone or with Irinotecamn or Oxaliplatin ± bevacizumab in patients with colorectal cancer.
Ongoing
Osteosarcoma
02383901ISO-MTX-OB1, A Retrospective Non-intervention Study tto investigate how rescue treatment with folates in patients with osteosarcoma works in clinical context. Clinical Trial >>
Results available
01987102ISO-MTX-003, Phase I/II study intended to identify the arfolitixorin (Modufolin®) dose to be used in continued clinical development for in the osteosarcoma indication. Clinical Trial >>
Completed