About Isofol

Isofol is a research-based biotechnology company working to improve the prognosis for patients with severe forms of cancer. The company’s drug candidate arfolitixorin aims to increase the effect of first-line standard treatments for several forms of solid tumors and is currently being studied in metastatic colorectal cancer, the world’s third most common cancer, where the medical need for better treatments is high.

Today’s standard of care for metastatic colorectal cancer is based on 5-FU – one of the world’s most widely used cancer drugs – and is given in combination with both folate and other drugs. Folate-based drugs are used to enhance the efficacy of 5-FU.

The drug candidate arfolitixorin is the first and only direct-acting folate that does not need to be converted in the body. Studies have shown that arfolitixorin results in higher concentrations in tumor tissue than existing drugs, and clinical data indicates promising effect.

We have strong potential to contribute something unique: a product that, when approved, can be integrated into a globally established treatment regimen for some of the world’s most common cancers. With patent protection through the 2040s and blockbuster potential exceeding SEK 10 billion, the conditions are in place for both scientific and commercial success.

Isofol Medical AB (publ) is traded on Nasdaq Stockholm.